The Chicago findings were based on new cases developing in an average 3.9-year interval between the baseline and follow-up examination among 815 men and women, black and white, aged 65 years and older. In the Chicago Health and Aging Project, persons in the highest category of vitamin E intake from food were 70% less likely than those in the lowest category of intake to be diagnosed with AD! The overall Chicago findings for vitamin C– which cranberries are very high in–were not statistically significant in this study but remain suggestive enough to be of interest for further study. The result was less clear, overall, with vitamin C. In both of these observational studies, higher dietary intake of antioxidants– especially vitamin E–was found to be associated with a lower risk of incident Alzheimer’s Disease (AD). Dietary Intake of Antioxidant Nutrients and the Risk of Incident Alzheimer Disease in a Biracial Community Study (pages 3230-3237).Dietary Intake of Antioxidants and Risk of Alzheimer Disease (pages 3223-3229).Several previous findings suggest that oxidative stress may play an important role in the development of AD, which is now the 6th-leading cause of death among adults, and is expected to afflict an estimated 14 million people within the next 50 years, leading some to call it the “health care challenge of the 21st century!” In the United States, the current estimate of 360,000 new cases of AD each year is expected to triple in the next 40 years! Even modestly effective interventions that delay the onset of this terrible disease by one to three years will substantially alleviate its growing economic and societal burden. The similarity of the results–which were generated using similar, standardized methods in Chicago (US) and Rotterdam (The Netherlands)–provides persuasive support for the idea that antioxidant-rich foods may have a beneficial impact on the development of Alzheimer’s disease (AD). The consistency of findings in these two independent cross-national studies is notable. Setapp subscribers also have access to SideNotes.Antioxidant Intake – Lower Risk of Alzheimer’s DiseaseĪn Examination of Two Studies Published by JAMA (The Journal of the American Medical Association) – June 26, 2002 A trial download version of the app is also available. The app is also available through the Apptorium website. SideNotes 1.1 is $19.99 and is available worldwide through the Mac App Store in the Productivity Category. Small bug fixes and performance enhancements.Fixed: Other application scrollbars were not working.Fixed: Escape key didn’t work properly during editing folder name.Fixed: URLs with a dash weren’t working.Fixed: On clickable elements in notes that were on screen bottom.AppleScript: ability to get current folder and selected note.Ability to set dark and light appearance manually.New keyboard shortcut to create a new note from pasteboard.New keyboard shortcut to move notes up and down.New keyboard shortcut to pin the app window.Dropping any file on the app will create a shortcut to that file with a preview.New option to show and hide the app – by clicking on a menubar icon.Version 1.1 brings numerous new and improved features: Notes can be grouped into folders, and each note can have one of six pre-set colors. Users can add a task by clicking the text formatting button or by using the key combo “CMD-T.” This creates a line with a checkmark, which can be marked as complete with a single mouse click. SideNotes also offers an accessible task list. The app also offers a Text Formatting button that displays a menu of various text formatting options. Formatting is rendered on the fly, allowing users to format text without knowing any complicated syntax. The app allows for both Markdown and plain text formatting, allowing users to quickly format text via Markdown syntax. Three text formatting modes are available: Markdown, Plain Text and Code.Create notes directly from the pasteboard.Save links, code snippets or even colors.Drag and drop pictures directly from a web browser.Mark notes with colors and group them into folders.Smoothly pull out notes from outside your monitor and easily hide them again.The app instantly appears, sliding over the other open windows with the click of a mouse or a quick keyboard combo. The application allows users to keep handy notes, graphics, task lists, and more without being distracted from their main workflow. SideNotes 1.1 hides on the side of your desktop when it’s not needed, and appears with a single click of the mouse. If you’re tired of searching through multiple windows to find your notes on your macOS desktop, independent development team Apptorium has a solution.
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